Demonstration Formulary
 
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4 Central nervous system

PALLIATIVE CARE PHYSICIANS - Guidelines for the use of drugs in symptom control

 

04-03-03 Selective serotonin re-uptake inhibitors

Fluoxetine
First Choice

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Sertraline
First Choice

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Citalopram
Formulary

Risk of QT prolongation

Link  MHRA: New maximum daily dose restrictions (including in elderly patients), contraindications, and warnings
Link  UKMI Q&A: What issues should be considered regarding drug induced QT prolongation?

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Citalopram
Formulary

4 drops (8 mg) is equivalent in therapeutic effect to 10mg tablet

Risk of QT prolongation

Link  MHRA: New maximum daily dose restrictions (including in elderly patients), contraindications, and warnings
Link  UKMI Q&A: What issues should be considered regarding drug induced QT prolongation?

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Fluoxetine
Formulary

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Paroxetine
Formulary

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Vortioxetine
Formulary

In line with NICE

Specialist initiation and stabilisation before transfer to Primary Care

Link  NICE TA367: Vortioxetine for treating major depressive episodes (Nov 2015)

Specialist initiation View adult BNF  View SPC online  View childrens BNF
Escitalopram Cipralex®
Non Formulary

Do not prescribe View adult BNF  View SPC online  View childrens BNF
Fluvoxamine Maleate Faverin®, Fluvoxamine®
Non Formulary

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